What is the advantage of capping the N and C termini of the peptide?
cGMP refers to the current Good Manufacturing Practice regulations enforced by the U. S. Food and Drug
Administration (FDA) Acetylation or capping of the N-terminus will make a peptide appear more like native protein. It
also helps to minimize amino peptidase degradation of the peptide. Amidation of the C terminus also helps to
stabilize the peptide from carboxypeptidase degradation.
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